| http://purl.uniprot.org/citations/17090927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17090927 | http://www.w3.org/2000/01/rdf-schema#comment | "Yeast Ino2p-Ino4p heterodimeric complex is well known as a transcriptional activator for the genes regulated by inositol and choline, such as the INO1 gene. Apl2p is a large subunit of the yeast adaptin complex, an adaptor complex required for the clathrin coat to bind to the membrane. We found that Ino2p, Ino4p, and Apl2p form a ternary complex. This interaction was initially observed in a yeast two-hybrid study and subsequently verified by co-immunoprecipitation. Ino2p and Ino4p bind to Apl2p in the same region of Apl2p, viz., at the middle part and the C-terminal part. Ino2p and Ino4p bind to Apl2p independently, but more strongly when both are present. Furthermore, a disruption of APL2 together with INO2 or INO4 rendered yeast cells sensitive to oxidative stress. INO2-APL2 double disruptants also showed growth inability in non-fermentable carbon sources, such as glycerol. These results indicate a genetic interaction between APL2, INO2 and INO4 and uncovere novel functions of the Ino2p-Ino4p-Apl2p complex in yeast."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.org/dc/terms/identifier | "doi:10.1271/bbb.60146"xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Ueda T."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Motomura M."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Nikawa J."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Yata M."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Miyoshi N."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/author | "Hisada D."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/name | "Biosci Biotechnol Biochem"xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/pages | "2604-2612"xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/title | "Ternary complex formation of Ino2p-Ino4p transcription factors and Apl2p adaptin beta subunit in yeast."xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://purl.uniprot.org/core/volume | "70"xsd:string |
| http://purl.uniprot.org/citations/17090927 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17090927 |
| http://purl.uniprot.org/citations/17090927 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17090927 |
| http://purl.uniprot.org/uniprot/#_P13902-mappedCitation-17090927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17090927 |
| http://purl.uniprot.org/uniprot/#_P26798-mappedCitation-17090927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17090927 |
| http://purl.uniprot.org/uniprot/#_P36000-mappedCitation-17090927 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17090927 |
| http://purl.uniprot.org/uniprot/P36000 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17090927 |
| http://purl.uniprot.org/uniprot/P26798 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17090927 |
| http://purl.uniprot.org/uniprot/P13902 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17090927 |