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http://purl.uniprot.org/citations/1709495http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1709495http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1709495http://www.w3.org/2000/01/rdf-schema#comment"The cloning of cDNAs encoding murine 2-5A synthetase has identified three related transcripts, represented by a previously described cDNA clone, L3 and two novel cDNAs, L1 and L2. L1 contains an open reading frame coding for a protein that shows 70% conservation at the amino acid level when compared to the protein predicted to be encoded by L3. L2 recognizes an IFN-induced transcript 600-bp larger than the L3 transcript. These three cDNAs map to a cosmid, cII, containing two murine 2-5A synthetase genes, ME12 and ME5/ME8, situated in a head-to-tail orientation separated by approximately 8 kb. Southern analyses of ME12 and ME5/ME8 using L3, L1-specific and L2-specific probes indicate that these genes have a similar organization. cII was transiently and stably transfected into CV-1 cells. When treated with interferon, the transfected cells produced mature, murine 2-5A synthetase transcripts identified using L3 and L2-specific probes. Thus all transcripts present in IFN-treated mouse cells which are recognized by the available murine 2-5A synthetase cDNA probes map to an approximately 40 kb region of the mouse genome containing two 2-5A synthetase genes."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.org/dc/terms/identifier"doi:10.1093/nar/19.8.1917"xsd:string
http://purl.uniprot.org/citations/1709495http://purl.org/dc/terms/identifier"doi:10.1093/nar/19.8.1917"xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Kumar A."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Kumar A."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Williams B.R.G."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Williams B.R.G."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Chebath J."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Chebath J."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Nissim A."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Nissim A."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Rutherford M.N."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/author"Rutherford M.N."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/name"Nucleic Acids Res."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/pages"1917-1924"xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/pages"1917-1924"xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/title"The murine 2-5A synthetase locus: three distinct transcripts from two linked genes."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/title"The murine 2-5A synthetase locus: three distinct transcripts from two linked genes."xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/volume"19"xsd:string
http://purl.uniprot.org/citations/1709495http://purl.uniprot.org/core/volume"19"xsd:string