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http://purl.uniprot.org/citations/17099065http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17099065http://www.w3.org/2000/01/rdf-schema#comment"Chandelier cells represent a unique type of cortical GABAergic interneuron whose axon terminals (Ch-terminals) form synapses exclusively with the axon initial segments of pyramidal cells. In this study, we have used immunocytochemistry for the high-affinity plasma membrane transporter-1 (GAT-1) to analyze the distribution and density of Ch-terminals in various cytoarchitectonic and functional areas of the human neocortex. The lowest density of GAT-1-immuoreactive (-ir) Ch-terminals was detected in the primary and secondary visual (areas 17 and 18) and in the somatosensory areas (areas 3b and 1). In contrast, an intermediate density was observed in the motor area 4 and the associative frontolateral areas 45 and 46, whereas the associative frontolateral areas 9 and 10, frontal orbitary areas 11, 12, 13, 14, and 47, associative temporal areas 20, 21, 22, and 38, and cingulate areas 24 and 32 displayed the highest density of GAT-1-ir Ch-terminals. Despite these differences, the laminar distribution of GAT-1-ir Ch-terminals was similar in most cortical areas. Hence, the highest density of this transporter was observed in layer II, followed by layers III, V, VI, and IV. In most cortical areas, the density of GAT-1-ir Ch-terminals was positively correlated with the neuronal density, although a negative correlation was detected in layer III across all cortical areas. These results indicate that there are substantial differences in the distribution and density of GAT-1-ir Ch-terminals between areas and layers of the human neocortex. These differences might be related to the different functional attributes of the cortical regions examined."xsd:string
http://purl.uniprot.org/citations/17099065http://purl.org/dc/terms/identifier"doi:10.1093/cercor/bhl114"xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/author"Munoz A."xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/author"Inda M.C."xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/author"Defelipe J."xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/name"Cereb Cortex"xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/pages"2060-2071"xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/title"The distribution of chandelier cell axon terminals that express the GABA plasma membrane transporter GAT-1 in the human neocortex."xsd:string
http://purl.uniprot.org/citations/17099065http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/17099065http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17099065
http://purl.uniprot.org/citations/17099065http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17099065
http://purl.uniprot.org/uniprot/#_A0A2R8Y4I3-mappedCitation-17099065http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17099065
http://purl.uniprot.org/uniprot/#_B7Z3C5-mappedCitation-17099065http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17099065
http://purl.uniprot.org/uniprot/#_P30531-mappedCitation-17099065http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17099065
http://purl.uniprot.org/uniprot/P30531http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17099065
http://purl.uniprot.org/uniprot/A0A2R8Y4I3http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17099065
http://purl.uniprot.org/uniprot/B7Z3C5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17099065