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http://purl.uniprot.org/citations/17100879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17100879http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17100879http://www.w3.org/2000/01/rdf-schema#comment"The immune system has evolved to tolerate what is self and reject what is foreign. The recognition of self from non-self is performed by activating and inhibitory receptors, which signal immune cells via adapter molecules, determining the outcome of the immune response. DAP10, a transmembrane adapter protein expressed broadly in hematopoietic cells, associates with NKG2D activating receptor forming a multisubunit complex, which recognizes self-proteins upregulated during tumorigenesis, infection, and autoimmune response. Analysis of immune reactions against syngeneic tumors, as well as autoimmune responses in the DAP10-deficient mice, revealed an important physiological role of DAP10 signaling in maintaining tolerance to self, probably by controlling the development and activation threshold of autoreactive T cells."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.org/dc/terms/identifier"doi:10.1111/j.1600-065x.2006.00456.x"xsd:string
http://purl.uniprot.org/citations/17100879http://purl.org/dc/terms/identifier"doi:10.1111/j.1600-065x.2006.00456.x"xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/author"Phillips J.H."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/author"Phillips J.H."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/author"Hyka-Nouspikel N."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/author"Hyka-Nouspikel N."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/date"2006"xsd:gYear
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/name"Immunol. Rev."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/name"Immunol. Rev."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/pages"106-117"xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/pages"106-117"xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/title"Physiological roles of murine DAP10 adapter protein in tumor immunity and autoimmunity."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/title"Physiological roles of murine DAP10 adapter protein in tumor immunity and autoimmunity."xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/volume"214"xsd:string
http://purl.uniprot.org/citations/17100879http://purl.uniprot.org/core/volume"214"xsd:string
http://purl.uniprot.org/citations/17100879http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17100879
http://purl.uniprot.org/citations/17100879http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17100879
http://purl.uniprot.org/citations/17100879http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17100879
http://purl.uniprot.org/citations/17100879http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17100879
http://purl.uniprot.org/uniprot/Q9QUJ0http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/17100879
http://purl.uniprot.org/uniprot/Q9QUJ0#attribution-8CD13A2B6BF656F79C4E9A3E6484AD71http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17100879