| http://purl.uniprot.org/citations/17101133 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17101133 | http://www.w3.org/2000/01/rdf-schema#comment | "Abl interactor (Abi) was identified as an Abl tyrosine kinase-binding protein and subsequently shown to be a component of the macromolecular Abi/WAVE complex, which is a key regulator of Rac-dependent actin polymerization. Previous studies showed that Abi-1 promotes c-Abl-mediated phosphorylation of Mammalian Enabled (Mena) and WAVE2. In addition to Abi-1, mammals possess Abi-2 and NESH (Abi-3). In this study, we compared the three Abi proteins in terms of the promotion of c-Abl-mediated phosphorylation and the formation of Abi/WAVE complex. Although Abi-2, like Abi-1, promoted the c-Abl-mediated phosphorylation of Mena and WAVE2, NESH (Abi-3) had no such effect. This difference was likely due to their binding abilities as to c-Abl. Immunoprecipitation revealed that NESH (Abi-3) is present in the Abi/WAVE complex. Our results suggest that NESH (Abi-3), like Abi-1 and Abi-2, is a component of the Abi/WAVE complex, but likely plays a different role in the regulation of c-Abl."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2006.10.065"xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Matsuda S."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Sato S."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Gotoh T."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Maruoka M."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Suzuki J."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Shishido T."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Tani K."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/author | "Hirao N."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/pages | "6464-6470"xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/title | "NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation."xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://purl.uniprot.org/core/volume | "580"xsd:string |
| http://purl.uniprot.org/citations/17101133 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17101133 |
| http://purl.uniprot.org/citations/17101133 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17101133 |
| http://purl.uniprot.org/uniprot/Q9NYB9#attribution-9078B7F35BC5E91C0AFFDE99273C29E6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/Q9NYB9#attribution-D7BD198E4455A5AA2801C9A0D2937204 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/Q9P2A4#attribution-9078B7F35BC5E91C0AFFDE99273C29E6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/Q9P2A4#attribution-D7BD198E4455A5AA2801C9A0D2937204 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/Q8IZP0#attribution-9078B7F35BC5E91C0AFFDE99273C29E6 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/Q8IZP0#attribution-D7BD198E4455A5AA2801C9A0D2937204 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |
| http://purl.uniprot.org/uniprot/P62484#attribution-178DF91E3E4154FD1902C13763B481EE | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17101133 |