| http://purl.uniprot.org/citations/17101473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17101473 | http://www.w3.org/2000/01/rdf-schema#comment | "This study investigated the genetic association of HLA class I genes and TNF-alpha microsatellites. HLA-A, -B, -C typing was carried out in 92 psoriasis vulgaris patients and 160 healthy individuals using a PCR-SSP method. 70 patients and 71 controls were typed for five microsatellite polymorphisms, TNFa-e. HLA-B*13 Cw*06, HLA-B*57 Cw*06 and HLA-B*39 Cw*12 haplotypes were found to be increased in patients with psoriasis type I when compared to controls, which could determine the susceptibility to development of psoriasis. TNFa4, TNFb1, TNFe1 and TNFa2 b1 c2 d4 e1 haplotypes showed a decreased frequency (p < 0.05) in psoriasis patients when compared to controls. HLA-B*13 allele and HLA-B*13 Cw*06, TNFa11 b4 c1 d3 e3 haplotypes showed increased frequencies (p < 0.05) in patients with type II psoriasis, which suggests susceptibility to the onset of psoriasis. Our results detected polymorphisms of the HLA class I and microsatellite TNF locus which could be markers of genetic predisposition to the disease."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Magalhaes R.F."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Donadi E.A."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Mendes-Junior C.T."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Simoes A.L."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Simoes R."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Kraemer M.H."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Biral A.C."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Tanaka A.M."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/author | "Wastowski I.J."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/date | "2006"xsd:gYear |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/name | "Eur J Dermatol"xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/pages | "523-529"xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/title | "Association of HLA-A, -B, -C genes and TNF microsatellite polymorphism with psoriasis vulgaris: a study of genetic risk in Brazilian patients."xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://purl.uniprot.org/core/volume | "16"xsd:string |
| http://purl.uniprot.org/citations/17101473 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17101473 |
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| http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-17101473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17101473 |
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| http://purl.uniprot.org/uniprot/#_A0A0A7C553-mappedCitation-17101473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17101473 |
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| http://purl.uniprot.org/uniprot/#_A0A0E3DCA0-mappedCitation-17101473 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17101473 |