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http://purl.uniprot.org/citations/1711047http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1711047http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1711047http://www.w3.org/2000/01/rdf-schema#comment"Two cDNA clones termed H36-1 and H36-2 were isolated from a human liver cDNA library. Clone H36-1 appears to represent the recently isolated human serum proteins h37 and h42, which are two differently glycosylated forms of a protein antigenically related to human complement factor H. The H36-1 deduced protein sequence is 327 amino acid long and possesses a leader sequence. The secreted part of the protein is comprised of five tandem repeating units, termed short consensus repeats (SCRs). SCR 1 and 2 display high homology to the corresponding region of the recently isolated murine factor H-related cDNA clone 13G1. In contrast, the 3'-end of the H36-1 clone shows sequence homology to the 3'-end of human complement factor H. The second clone, H36-2, is nearly identical to H36-1. Within 1148 base pairs, where the two clones overlap, their nucleotide sequences differed at nine positions. One nucleotide exchange in the sequence of H36-2 which was located within SCR 1 creats a stop codon (TAA). Consequently, the corresponding mRNA cannot code for a functional protein, suggesting that this clone is a transcribed pseudogene. These two clones represent new human members of the family of proteins structurally related to complement factor H."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)99058-7"xsd:string
http://purl.uniprot.org/citations/1711047http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)99058-7"xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Horstmann R.D."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Horstmann R.D."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Skerka C."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Skerka C."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Zipfel P.F."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/author"Zipfel P.F."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/pages"12015-12020"xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/pages"12015-12020"xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/title"Molecular cloning of a human serum protein structurally related to complement factor H."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/title"Molecular cloning of a human serum protein structurally related to complement factor H."xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/volume"266"xsd:string
http://purl.uniprot.org/citations/1711047http://purl.uniprot.org/core/volume"266"xsd:string
http://purl.uniprot.org/citations/1711047http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1711047
http://purl.uniprot.org/citations/1711047http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1711047
http://purl.uniprot.org/citations/1711047http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1711047
http://purl.uniprot.org/citations/1711047http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1711047