| http://purl.uniprot.org/citations/17119116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17119116 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously reported a lower risk of non-Hodgkin lymphoma (NHL) associated with high consumption of vitamin B6 and methionine, dietary determinants of one-carbon metabolism. Evidence has linked genetic variants involved in one-carbon metabolism to NHL. We investigated 30 polymorphisms in 18 genes for their main effect on NHL among 1141 incident cases and 949 population-based controls and examined gene-nutrient interactions in a subgroup of 386 cases and 319 controls who provided detailed food-frequency information. Odds ratios (ORs) and 95% confidence intervals (CIs) were adjusted for age, sex, and race. We observed a decreased risk of NHL over-all with BHMTEx8+453A>T and increased risk with CBS Ex13+41C>T, FPGS Ex15-263T>C, and SHMT1 Ex12+138C>T and Ex12+236C>T. Furthermore, significant gene-nutrient interactions limited the protective association comparing high versus low vitamin B6 to FPGS Ex15-263T>C CC (OR = 0.22; 95% CL = 0.10-0.52), MTHFS IVS2-1411T>G TT/TG (OR = 0.54; 95% CI = 0.36-0.81), and MTR Ex26-20A>G AA (OR = 0.55; 95% CI = 0.35-0.86) genotypes, and the protective association of methionine to FTHFD Ex10-40G>TGG (OR = 0.63; 95% CI = 0.44-0.91), MTHFR Ex8-62A>C CC (OR = 0.13; 95% CI = 0.04-0.39), and MTRR Ex5+136T>CTT (OR = 0.67; 95% CI = 0.47-0.97) genotypes. Warranting replication, our finding of gene-nutrient interactions in one-carbon metabolism supports their etiologic involvement in lymphomagenesis."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.org/dc/terms/identifier | "doi:10.1182/blood-2006-07-034330"xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Lan Q."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Wang S.S."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Davis S."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Hartge P."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Chanock S."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Blair A."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Cozen W."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Schenk M."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Rothman N."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Kelemen L.E."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/author | "Lim U."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/pages | "3050-3059"xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/title | "Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study."xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://purl.uniprot.org/core/volume | "109"xsd:string |
| http://purl.uniprot.org/citations/17119116 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17119116 |
| http://purl.uniprot.org/citations/17119116 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17119116 |
| http://purl.uniprot.org/uniprot/#_A0A1C9J7R9-mappedCitation-17119116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17119116 |
| http://purl.uniprot.org/uniprot/#_A0A1W5XGE6-mappedCitation-17119116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17119116 |
| http://purl.uniprot.org/uniprot/#_A0A482KFZ6-mappedCitation-17119116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17119116 |
| http://purl.uniprot.org/uniprot/#_A0A4P8L6T5-mappedCitation-17119116 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17119116 |