http://purl.uniprot.org/citations/17123957 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17123957 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17123957 | http://www.w3.org/2000/01/rdf-schema#comment | "Poxviruses encode immuno-modulatory proteins capable of subverting host defenses. The poxvirus vaccinia expresses a small 14-kDa protein, N1L, that is critical for virulence. We report the crystal structure of N1L, which reveals an unexpected but striking resemblance to host apoptotic regulators of the B cell lymphoma-2 (Bcl-2) family. Although N1L lacks detectable Bcl-2 homology (BH) motifs at the sequence level, we show that N1L binds with high affinity to the BH3 peptides of pro-apoptotic Bcl-2 family proteins in vitro, consistent with a role for N1L in modulating host antiviral defenses."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.org/dc/terms/identifier | "doi:10.1110/ps.062454707"xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.org/dc/terms/identifier | "doi:10.1110/ps.062454707"xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Aleshin A.E."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Aleshin A.E."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Liddington R.C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Liddington R.C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Stec B."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Stec B."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Reed J.C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Reed J.C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Aoyagi M."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Aoyagi M."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Jin C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Jin C."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Zhai D."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/author | "Zhai D."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/name | "Protein Sci."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/name | "Protein Sci."xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/pages | "118-124"xsd:string |
http://purl.uniprot.org/citations/17123957 | http://purl.uniprot.org/core/pages | "118-124"xsd:string |