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http://purl.uniprot.org/citations/17133603 | http://www.w3.org/2000/01/rdf-schema#comment | "Previous data showed that complexin I, a SNARE regulatory protein, is localized in and/or around the acrosome and is necessary for the acrosome reaction in sperm. To understand how complexin I regulates the acrosome reaction, we used complexin-GST pulldown assays to identify interacting proteins. We showed that both complexins I and II bound mouse sperm dynamin 2. Dynamin 2 is a 100 kDa GTPase essential to many aspects of endocytosis but its potential role in exocytosis is unknown. Dynamin 2 is expressed in rat testis and widely expressed in other tissues; however, the function of dynamin 2 in germ cells is uncertain. Dynamin 2 protein was detected in mouse testis and was most abundant in or around the developing acrosome of spermatids. In addition, dynamin 2 was co-localized with complexin I in the acrosomal region of mammalian sperm. Its co-localization and interaction with complexin I suggest that dynamin 2 may play a role during acrosome formation and/or acrosomal exocytosis."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.org/dc/terms/identifier | "doi:10.1002/mrd.20660"xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/author | "Li L."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/author | "Shi X."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/author | "Zhao L."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/author | "Miller D.J."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/name | "Mol Reprod Dev"xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/pages | "750-757"xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/title | "Dynamin 2 associates with complexins and is found in the acrosomal region of mammalian sperm."xsd:string |
http://purl.uniprot.org/citations/17133603 | http://purl.uniprot.org/core/volume | "74"xsd:string |
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