| http://purl.uniprot.org/citations/1717323 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1717323 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1717323 | http://www.w3.org/2000/01/rdf-schema#comment | "POU domain genes have been shown to be important in tissue-specific gene regulation during development. We have cloned cDNA's encoding two unique Xenopus laevis POU-domain proteins, XLPOU 1 and XLPOU 2. Sequencing revealed that the POU domain of both of these genes have greater than 90% homology with that of the POU III class of proteins. XLPOU 1 gene expression begins at the neural plate stage, while XLPOU 2 gene expression is first detected at the neurula stage; both XLPOU 1 and XLPOU 2 transcripts continue to be expressed throughout development. In adults, XLPOU 1 expression is restricted to the skin and brain, while XLPOU 2 is observed in the kidney and brain. In dissected embryos, both XLPOU 1 and XLPOU 2 are expressed in the dorsoanterior portion of an early tailbud embryo. Consistent with this localization, uv treatment, a condition that "posteriorizes" embryos, greatly reduces the expression of XLPOU 1 and XLPOU 2. Whole-mount in situ hybridization demonstrates that at the neural fold stage, XLPOU 1 transcripts appear to be localized primarily in the anterior neural plate. In sections of embryos, in situ hybridization shows that XLPOU 1 transcripts are localized mostly in the anterior region of the nerve cord of neurula stage embryos. In tailbud stage embryos, the XLPOU 1 transcripts are found predominantly in the eye and brain, with weak expression along the length of the nerve cord. We believe that XLPOU 1 and XLPOU 2, because of their localized and early expression in embryos, may play an important role in the specification of neuronal phenotypes."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.org/dc/terms/identifier | "doi:10.1016/0012-1606(91)90294-d"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.org/dc/terms/identifier | "doi:10.1016/0012-1606(91)90294-d"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/author | "Sato S.M."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/author | "Sato S.M."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/author | "Agarwal V.R."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/author | "Agarwal V.R."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/date | "1991"xsd:gYear |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/pages | "363-373"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/pages | "363-373"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/title | "XLPOU 1 and XLPOU 2, two novel POU domain genes expressed in the dorsoanterior region of Xenopus embryos."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/title | "XLPOU 1 and XLPOU 2, two novel POU domain genes expressed in the dorsoanterior region of Xenopus embryos."xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/volume | "147"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://purl.uniprot.org/core/volume | "147"xsd:string |
| http://purl.uniprot.org/citations/1717323 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1717323 |
| http://purl.uniprot.org/citations/1717323 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1717323 |
| http://purl.uniprot.org/citations/1717323 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1717323 |
| http://purl.uniprot.org/citations/1717323 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1717323 |
| http://purl.uniprot.org/embl-cds/CAA41781.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1717323 |
| http://purl.uniprot.org/uniprot/P31364 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/1717323 |