http://purl.uniprot.org/citations/17180083 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17180083 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17180083 | http://www.w3.org/2000/01/rdf-schema#comment | "A systematic search for genes differentially expressed in human tissues resulted in the isolation of a gene encoding a protein with high homology to DNase I. In addition to the recently described cDNA sequence (Parrish et al., 1995) we have isolated a transcript, alternatively spliced in the 5' noncoding region. The gene is located between the QM and the XAP-2 gene in Xq28 and encodes a 302 amino acid protein with 39% identity to human DNase I. Besides a high homology at the nucleotide and amino acid level, most exon-intron boundaries of DNase I and DNase X are identical, indicating that both genes may have evolved from a common ancestor. The predicted function was verified by expression of a recombinant protein in an inducible bacterial system and detection of DNase activity. In contrast to DNase I a 18 kdal amino terminal fragment of the full length 35 kdal protein exhibited DNase activity."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Delius H."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Delius H."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Poustka A."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Poustka A."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Zentgraf H."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Zentgraf H."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Coy J.F."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Coy J.F."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Himmele R."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Himmele R."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Velhagen I."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/author | "Velhagen I."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/date | "1996"xsd:gYear |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/name | "Cell Death Differ."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/name | "Cell Death Differ."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/pages | "199-206"xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/pages | "199-206"xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/title | "Isolation, differential splicing and protein expression of a DNase on the human X chromosome."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/title | "Isolation, differential splicing and protein expression of a DNase on the human X chromosome."xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/volume | "3"xsd:string |
http://purl.uniprot.org/citations/17180083 | http://purl.uniprot.org/core/volume | "3"xsd:string |