RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/1718973http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1718973http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1718973http://www.w3.org/2000/01/rdf-schema#comment"A 39-kDa protein of unknown function has previously been reported to copurify with the low density lipoprotein receptor-related protein (LRP)/alpha 2-macroglobulin receptor. In this study we demonstrate that a recombinant 39-kDa fusion protein can reversibly bind to the 515-kDa subunit of the LRP/alpha 2-macroglobulin receptor. This interaction inhibits the binding and uptake of the receptor's two known ligands: 1) beta-migrating very low density lipoproteins activated by enrichment with apoprotein E and 2) alpha 2-macroglobulin activated by incubation with plasma proteases or methylamine. A potential in vivo role of the 39-kDa protein is to modulate the uptake of apoE-enriched lipoproteins and activated alpha 2-macroglobulin in hepatic and extrahepatic tissues."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)54845-6"xsd:string
http://purl.uniprot.org/citations/1718973http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(18)54845-6"xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Herz J."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Herz J."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Brown M.S."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Brown M.S."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Goldstein J.L."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Goldstein J.L."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Ho Y.K."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Ho Y.K."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Strickland D.K."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/author"Strickland D.K."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/pages"21232-21238"xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/pages"21232-21238"xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/title"39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/title"39-kDa protein modulates binding of ligands to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor."xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/volume"266"xsd:string
http://purl.uniprot.org/citations/1718973http://purl.uniprot.org/core/volume"266"xsd:string