| http://purl.uniprot.org/citations/17199048 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17199048 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila PAN GU (PNG) kinase complex regulates the developmental translation of cyclin B. cyclin B mRNA becomes unmasked during oogenesis independent of PNG activity, but PNG is required for translation from egg activation. We find that although polyadenylation of cyclin B augments translation, it is not essential, and a fully elongated poly(A) is not required for translation to proceed. In fact, changes in poly(A) tail length are not sufficient to account for PNG-mediated control of cyclin B translation and of the early embryonic cell cycles. We present evidence that PNG functions instead as an antagonist of PUMILIO-dependent translational repression. Our data argue that changes in poly(A) tail length are not a universal mechanism governing embryonic cell cycles, and that PNG-mediated derepression of translation is an important alternative mechanism in Drosophila."xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2006.10.017"xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/author | "Vardy L."xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/author | "Orr-Weaver T.L."xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/name | "Dev Cell"xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/pages | "157-166"xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/title | "The Drosophila PNG kinase complex regulates the translation of cyclin B."xsd:string |
| http://purl.uniprot.org/citations/17199048 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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