| http://purl.uniprot.org/citations/17223267 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17223267 | http://www.w3.org/2000/01/rdf-schema#comment | "Long-term potentiation (LTP) is a persistent increase in the strength of synaptic transmission triggered by neuronal activity. Here, we submitted hippocampal slices to a perfusion of forskolin and IBMX, which induces a long-lasting LTP (>4 h) (L-LTP). We separated the proteins of the CA1 region by two-dimensional gel electrophoresis (2-DE). We then immunoblotted them using an anti-p-Tyr antibody. We found a protein whose tyrosine phosphorylation was unchanged 10 min after LTP induction but was dramatically increased after 1h, dropping back to its baseline after 4 h. This protein was identified as rabphilin using matrix-assisted laser desorption ionisation-time of flight mass spectrometry (MALDI-TOF MS). We also demonstrated that genistein, an inhibitor of tyrosine phosphorylation, prevented the development of the late phase of electrically-induced L-LTP. Our results suggest that rabphilin, a protein present in presynaptic terminals, could play a role in the late phase of L-LTP."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.neulet.2006.12.031"xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/author | "Wattiez R."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/author | "Godaux E."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/author | "Ris L."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/author | "Capron B."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/author | "Sindic C."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/pages | "257-262"xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/title | "Tyrosine phosphorylation of rabphilin during long-lasting long-term potentiation."xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://purl.uniprot.org/core/volume | "414"xsd:string |
| http://purl.uniprot.org/citations/17223267 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17223267 |
| http://purl.uniprot.org/citations/17223267 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17223267 |
| http://purl.uniprot.org/uniprot/#_Q768S5-mappedCitation-17223267 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17223267 |
| http://purl.uniprot.org/uniprot/#_P47708-mappedCitation-17223267 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17223267 |
| http://purl.uniprot.org/uniprot/P47708 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17223267 |
| http://purl.uniprot.org/uniprot/Q768S5 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17223267 |