| http://purl.uniprot.org/citations/17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17236237 | http://www.w3.org/2000/01/rdf-schema#comment | "Murine natural killer (NK) cells are inhibited by target cell MHC class I molecules via Ly49 receptors. However, Ly49 receptors can be made inaccessible to target cell MHC class I by a cis interaction with its MHC class I ligand within the NK cell membrane. It has recently been demonstrated that MHC class I proteins transfer from the target cells to the NK cell. Here, we establish that the number of transferred MHC class I proteins is proportional to the number of Ly49A receptors at the NK cell surface. Ly49A+ NK cells from mice expressing the Ly49A ligand H-2D(d) showed a 90% reduction in Ly49A accessibility compared to Ly49A+ NK cells from H-2D(d)-negative mice. The reduction was caused both by lower expression of Ly49A and interactions in cis between Ly49A and H-2D(d) at the NK cell surface. Approximately 75% of the Ly49A receptors on H-2D(d)-expressing NK cells were occupied in cis with endogenous H-2D(d) and only 25% were free to interact with H-2D(d) molecules in trans. Thus, H-2D(d) ligands control Ly49A receptor accessibility through interactions both in cis and in trans."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.200636693"xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/author | "Davis D.M."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/author | "Andersson K.E."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/author | "Hoglund P."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/author | "Williams G.S."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/name | "Eur J Immunol"xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/pages | "516-527"xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/title | "Quantifying the reduction in accessibility of the inhibitory NK cell receptor Ly49A caused by binding MHC class I proteins in cis."xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/17236237 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17236237 |
| http://purl.uniprot.org/citations/17236237 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17236237 |
| http://purl.uniprot.org/uniprot/#_A0A0F6Q910-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_B7ZN08-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_Q925C6-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_P20937-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
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| http://purl.uniprot.org/uniprot/#_Q60968-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_Q8MHR8-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_Q8MHV1-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
| http://purl.uniprot.org/uniprot/#_Q8MHV3-mappedCitation-17236237 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17236237 |
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