| http://purl.uniprot.org/citations/17264129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17264129 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17264129 | http://www.w3.org/2000/01/rdf-schema#comment | "Characterization of spliceosomal complexes in the fission yeast Schizosaccharomyces pombe revealed particles sedimenting in the range of 30-60S, exclusively containing U1 snRNA. Here, we report the tandem affinity purification (TAP) of U1-specific protein complexes. The components of the complexes were identified using (LC-MS/MS) mass spectrometry. The fission yeast U1 snRNP contains 16 proteins, including the 7 Sm snRNP core proteins. In both fission and budding yeast, the U1 snRNP contains 9 and 10 U1 specific proteins, respectively, whereas the U1 particle found in mammalian cells contains only 3. Among the U1-specific proteins in S. pombe, three are homolog to the mammalian and six to the budding yeast Saccharomyces cerevisiae U1-specific proteins, whereas three, called U1H, U1J and U1L, are proteins specific to S. pombe. Furthermore, we demonstrate that the homolog of U1-70K and the three proteins specific to S. pombe are essential for growth. We will discuss the differences between the U1 snRNPs with respect to the organism-specific proteins found in the two yeasts and the resulting effect it has on pre-mRNA splicing."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkl1144"xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkl1144"xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Wehland J."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Wehland J."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Wissing J."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Wissing J."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Jaensch L."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Jaensch L."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Kaeufer N.F."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Kaeufer N.F."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Luetzelberger M."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Luetzelberger M."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Bottner C.A."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Bottner C.A."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Newo A.N.S."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/author | "Newo A.N.S."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/name | "Nucleic Acids Res."xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/pages | "1391-1401"xsd:string |
| http://purl.uniprot.org/citations/17264129 | http://purl.uniprot.org/core/pages | "1391-1401"xsd:string |