| http://purl.uniprot.org/citations/17267406 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17267406 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17267406 | http://www.w3.org/2000/01/rdf-schema#comment | "In Caenorhabditis elegans, the Mex-3 protein is a translational regulator that specifies the posterior blastomere identity in the early embryo and contributes to the maintenance of the germline totipotency. We have now identified a family of four homologous human Mex-3 genes, called hMex-3A to -3D that encode proteins containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. The hMex-3 are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1-dependent export pathway. Our analysis further revealed that hMex-3A and hMex-3B, but not hMex-3C, colocalize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover. Taken together, these findings indicate that hMex-3 proteins constitute a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkm016"xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkm016"xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Duret L."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Duret L."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Seraphin B."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Seraphin B."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Billaud M."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Billaud M."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Le Hir H."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Le Hir H."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Domon-Dell C."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Domon-Dell C."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Freund J.-N."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Freund J.-N."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Buchet-Poyau K."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Buchet-Poyau K."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Courchet J."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Courchet J."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Scoazec J.-Y."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/author | "Scoazec J.-Y."xsd:string |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17267406 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |