| http://purl.uniprot.org/citations/17268553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17268553 | http://www.w3.org/2000/01/rdf-schema#comment | "Our current knowledge of the general factor requirement in transcription by the three mammalian RNA polymerases is based on a small number of model promoters. Here, we present a comprehensive chromatin immunoprecipitation (ChIP)-on-chip analysis for 28 transcription factors on a large set of known and novel TATA-binding protein (TBP)-binding sites experimentally identified via ChIP cloning. A large fraction of identified TBP-binding sites is located in introns or lacks a gene/mRNA annotation and is found to direct transcription. Integrated analysis of the ChIP-on-chip data and functional studies revealed that TAF12 hitherto regarded as RNA polymerase II (RNAP II)-specific was found to be also involved in RNAP I transcription. Distinct profiles for general transcription factors and TAF-containing complexes were uncovered for RNAP II promoters located in CpG and non-CpG islands suggesting distinct transcription initiation pathways. Our study broadens the spectrum of general transcription factor function and uncovers a plethora of novel, functional TBP-binding sites in the human genome."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.org/dc/terms/identifier | "doi:10.1038/sj.emboj.7601550"xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Stunnenberg H."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Grummt I."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Denissov S."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Voit R."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Hernandez N."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "van Driel M."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Hekkelman M."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Hulsen T."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/author | "Wehrens R."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/pages | "944-954"xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/title | "Identification of novel functional TBP-binding sites and general factor repertoires."xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://purl.uniprot.org/core/volume | "26"xsd:string |
| http://purl.uniprot.org/citations/17268553 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17268553 |
| http://purl.uniprot.org/citations/17268553 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17268553 |
| http://purl.uniprot.org/uniprot/#_Q15572-mappedCitation-17268553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17268553 |
| http://purl.uniprot.org/uniprot/#_A0A804HLG9-mappedCitation-17268553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17268553 |
| http://purl.uniprot.org/uniprot/#_P20226-mappedCitation-17268553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17268553 |
| http://purl.uniprot.org/uniprot/#_Q16514-mappedCitation-17268553 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17268553 |
| http://purl.uniprot.org/uniprot/Q15572 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17268553 |
| http://purl.uniprot.org/uniprot/Q16514 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17268553 |