| http://purl.uniprot.org/citations/17299780 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17299780 | http://www.w3.org/2000/01/rdf-schema#comment | "The mechanisms of agonist-induced calcium entry (ACE) following depletion of intracellular calcium stores have not been fully established. We report here that calcium-independent phospholipase A (iPLA(2)) is required for robust Ca(2+) entry in HaCaT keratinocytes following ATP or UTP stimulation. Lysophosphatidic acid (LPA), an unrelated agonist, evoked Ca(2+) release without inducing robust Ca(2+) entry. Both LPA and UTP induced the redistribution of STIM1 into puncta which localized to regions near or at the plasma membrane, as well as within the cytoplasm. Plasma membrane-associated STIM1 remained high for up to 10 min after UTP stimulation, whereas it had returned almost to baseline by that time point in LPA-stimulated cells. This correlated with faster reloading of the endoplasmic reticulum Ca(2+) stores in LPA treated cells. Thus by differentially regulating store-refilling after agonist-mediated depletion, LPA and UTP may exert distinct effects on the duration of STIM1 localization at the plasma membrane, and thus, on the magnitude and duration of ACE."xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.org/dc/terms/identifier | "doi:10.1002/jcp.20993"xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/author | "Whitaker M."xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/author | "Ross K."xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/author | "Reynolds N.J."xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/name | "J Cell Physiol"xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/pages | "569-576"xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/title | "Agonist-induced calcium entry correlates with STIM1 translocation."xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://purl.uniprot.org/core/volume | "211"xsd:string |
| http://purl.uniprot.org/citations/17299780 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17299780 |
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| http://purl.uniprot.org/uniprot/G0XQ39 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17299780 |
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