| http://purl.uniprot.org/citations/1730258 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1730258 | http://www.w3.org/2000/01/rdf-schema#comment | "The VpreB1 protein is thought to be expressed on the surface of pre-B cells in association with lambda 5 and mu heavy chain, and to play an important role on B cell differentiation. The expression of VpreB1 and lambda 5 is pre-B cell specific, and regulated at the initiation of transcription. We have identified at least two sequence-specific DNA-binding proteins which bind to the region -191 to -74 of the promoter of the mouse VpreB1 gene. These DNA-binding proteins also bind to the promoter of the mouse lambda 5 gene. One of the two DNA-binding proteins, called EBB-1, is restricted to pre-B and B cells, but not detected in plasma cells, T cells and cells of other lineages. Transient transfection analysis of reporter constructs revealed that the binding sites of these proteins play a significant role in the activity of the promoter, especially the binding site of EBB-1. Taken together these results suggest that EBB-1 might be one of the crucial factors which regulates a series of intracellular events in B cell differentiation."xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.org/dc/terms/identifier | "doi:10.1002/eji.1830220107"xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/author | "Watanabe T."xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/author | "Kudo A."xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/author | "Okabe T."xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/name | "Eur J Immunol"xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/pages | "37-43"xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/title | "A pre-B- and B cell-specific DNA-binding protein, EBB-1, which binds to the promoter of the VpreB1 gene."xsd:string |
| http://purl.uniprot.org/citations/1730258 | http://purl.uniprot.org/core/volume | "22"xsd:string |
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| http://purl.uniprot.org/uniprot/#_G3UYK4-mappedCitation-1730258 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730258 |
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