| http://purl.uniprot.org/citations/1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/1730621 | http://www.w3.org/2000/01/rdf-schema#comment | "The gene that encodes a proteoglycan peptide core rich in serine and glycine (SG-PG) is selectively expressed by hematopoietic cells that store in their cytoplasmic granules negatively charged proteoglycans bound ionically to numerous positively charged proteins. With deletion analysis, a negative transcription regulatory element was located between residues -250 and -190 of the 5'-flanking region of the mouse SG-PG gene, and a positive regulatory element was located between residues -118 and -81. The negative regulatory element was dominantly active in fibroblasts that do not express the SG-PG gene whereas the positive regulatory element was dominantly active in hematopoietic cells that do express the SG-PG gene. Site-directed mutagenesis was used to demonstrate that the proximal element within the gene's atypical promoter resided between residues -40 and -20. As assessed by gel mobility shift analyses, the nuclei of rat basophilic leukemia-1 cells and rat-1 fibroblasts contain a number of trans-acting factors that interact with the positive and negative cis-acting regulatory elements of the SG-PG gene. Furthermore, some of these trans-acting factors appear to be different for the two cell types. These studies on cell types that do and do not express the SG-PG gene indicate that transcription of this proteoglycan peptide core gene is regulated constitutively by both positive and negative cis-acting elements located 5' of an atypical promoter."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(18)48538-9"xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/author | "Avraham H."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/author | "Stevens R.L."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/author | "Austen K.F."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/author | "Avraham S."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/date | "1992"xsd:gYear |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/pages | "610-617"xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/title | "Negative and positive cis-acting elements in the promoter of the mouse gene that encodes the serine/glycine-rich peptide core of secretory granule proteoglycans."xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://purl.uniprot.org/core/volume | "267"xsd:string |
| http://purl.uniprot.org/citations/1730621 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/1730621 |
| http://purl.uniprot.org/citations/1730621 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/1730621 |
| http://purl.uniprot.org/uniprot/#_E0CYA5-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_E0CZH1-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_A0A338P6T2-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_A0A338P6W0-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_A0A338P6X4-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_A0A338P676-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_D6RCG1-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_P13609-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_Q64737-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_Q3TH49-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |
| http://purl.uniprot.org/uniprot/#_Q3UJP8-mappedCitation-1730621 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/1730621 |