| http://purl.uniprot.org/citations/17340018 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17340018 | http://www.w3.org/2000/01/rdf-schema#comment | "The PSORS1 locus is the consistently replicated genetic risk factor for psoriasis. Clinical associations with the main marker allele of PSORS1, HLA-Cw6, have been addressed in a number of studies, but clinical associations have not been used as a way to distinguish the effects of the neighbouring candidate genes in PSORS1. Our results show that HLA-Cw6 and CCHCR1 risk allele associations with clinical features of psoriasis are predictably highly similar in a Finnish nationwide cohort of 379 psoriasis patients. The clinical profiling of a small group of patients (n=34) who were HLA-Cw6-but CCHCR1*WWCC positive suggested that no great differences existed between them and HCR-Cw6-patients. HCR+ genotype (as well as Cw6+ genotype) correlated for the first time positively with female sex and, in contrast with previous studies, negatively with disease severity. Presence of psoriatic arthritis was more pronounced in HCR- psoriasis (as well as in Cw6-psoriasis). Clinical profiling may be a useful approach to distinguishing genetic effects of candidate genes even within a locus in sufficiently large cohorts."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.org/dc/terms/identifier | "doi:10.2340/00015555-0184"xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Kere J."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Reunala T."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Elomaa O."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Karvonen J."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Karvonen S.L."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Saarialho-Kere U."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Snellman E."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Suomela S."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Uurasmaa T."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Jansen C.T."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Onkamo P."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Holopainen P."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Tiala I."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Himberg J."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Kainu K."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Kivikas K."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/author | "Koskinen L."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/name | "Acta Derm Venereol"xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/pages | "127-134"xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/title | "Clinical associations of the risk alleles of HLA-Cw6 and CCHCR1*WWCC in psoriasis."xsd:string |
| http://purl.uniprot.org/citations/17340018 | http://purl.uniprot.org/core/volume | "87"xsd:string |