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http://purl.uniprot.org/citations/17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17366633http://www.w3.org/2000/01/rdf-schema#comment"Galectin-1 has been implicated in the development of skeletal muscle, being maximally expressed at the time of myofiber formation. Furthermore, in the presence of exogenous galectin-1, mononuclear myoblasts show increased fusion in vitro. In the current study, we have used the galectin-1 null mouse to elucidate the role of galectin-1 in skeletal muscle development and regeneration. Myoblasts derived from the galectin-1 mutant showed a reduced ability to fuse in vitro. In galectin-1 null mutants, there was evidence of a delay in muscle fiber development at the neonatal stage and muscle fiber diameter was reduced when compared with wild-type at the adult stage. Muscle regeneration was also compromised in the galectin-1 mutant with the process being delayed and a reduced fiber size being maintained. These results, therefore, show a definitive role for galectin-1 in fusion of myoblasts both in vitro, in vivo, and in regeneration after recovery from induced injury."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.org/dc/terms/identifier"doi:10.1002/dvdy.21123"xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Prasad R."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Deltour L."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Stewart H.J."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Poirier F."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Goldring K."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Georgiadis V."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Horwood J."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Lawrence-Watt D.J."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Pollard H.J."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/author"Tavsanoglu Y."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/name"Dev Dyn"xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/pages"1014-1024"xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/title"Lack of galectin-1 results in defects in myoblast fusion and muscle regeneration."xsd:string
http://purl.uniprot.org/citations/17366633http://purl.uniprot.org/core/volume"236"xsd:string
http://purl.uniprot.org/citations/17366633http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17366633
http://purl.uniprot.org/citations/17366633http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17366633
http://purl.uniprot.org/uniprot/#_A0A2R8VHJ0-mappedCitation-17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17366633
http://purl.uniprot.org/uniprot/#_A2RSK4-mappedCitation-17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17366633
http://purl.uniprot.org/uniprot/#_P16045-mappedCitation-17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17366633
http://purl.uniprot.org/uniprot/#_P24699-mappedCitation-17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17366633
http://purl.uniprot.org/uniprot/#_Q8VHZ2-mappedCitation-17366633http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17366633