| http://purl.uniprot.org/citations/17401378 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17401378 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17401378 | http://www.w3.org/2000/01/rdf-schema#comment | "Biogenesis of iron-sulfur ([Fe-S]) proteins in eukaryotes requires the function of complex proteinaceous machineries in both mitochondria and cytosol. In contrast to the mitochondrial pathway, little is known about [Fe-S] protein assembly in the cytosol. So far, four highly conserved proteins (Cfd1, Nbp35, Nar1 and Cia1) have been identified as members of the cytosolic [Fe-S] protein assembly machinery, but their molecular function is unresolved. Using in vivo and in vitro approaches, we found that the soluble P-loop NTPases Cfd1 and Nbp35 form a complex and bind up to three [4Fe-4S] clusters, one at the N terminus of Nbp35 and one each at a new C-terminal cysteine-rich motif present in both proteins. These labile [Fe-S] clusters can be rapidly transferred and incorporated into target [Fe-S] apoproteins in a Nar1- and Cia1-dependent fashion. Our data suggest that the Cfd1-Nbp35 complex functions as a novel scaffold for [Fe-S] cluster assembly in the eukaryotic cytosol."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.org/dc/terms/identifier | "doi:10.1038/nchembio872"xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.org/dc/terms/identifier | "doi:10.1038/nchembio872"xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Lill R."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Lill R."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Pierik A.J."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Pierik A.J."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Muehlenhoff U."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Muehlenhoff U."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Netz D.J.A."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Netz D.J.A."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Stuempfig M."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/author | "Stuempfig M."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/name | "Nat. Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/name | "Nat. Chem. Biol."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/pages | "278-286"xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/pages | "278-286"xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/title | "The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/title | "The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol."xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/volume | "3"xsd:string |
| http://purl.uniprot.org/citations/17401378 | http://purl.uniprot.org/core/volume | "3"xsd:string |