http://purl.uniprot.org/citations/17415682 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17415682 | http://www.w3.org/2000/01/rdf-schema#comment | "The human STYK1/NOK protein is approximately 30-35% similar to mouse fibroblast growth factor receptor 3 and a kinase homologue in D. melanogaster in the tyrosine protein kinase region. STYK1/NOK was identified as being up regulated in MDA-MB-231, an estrogen receptor-alpha negative breast cancer cell line, following 12 h of estrogen treatment at 1x10(-9) M. On further investigation of STYK1/NOK in estrogen treated cell line MDA-MB-231, STYK1/NOK was up regulated at 6 h post treatment when compared to untreated cells. We also investigated the expression levels of STYK1/NOK in other breast cancer cell lines MCF-7, MDA-MB-231, BT-549, and MDA-MB-435S using QRT-PCR. In addition, the analysis of message accumulation was increased with other synthetic estrogen response modifiers. We propose that the regulation of STYK1/NOK is achieved independent of ERalpha and suggests further investigation to the relevance of this kinase in breast cancer progression."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11033-006-9047-1"xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/author | "Freeman S."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/author | "Moore J.A."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/author | "Kimbro K.S."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/author | "Willard M."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/author | "Duschene K."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/date | "2008"xsd:gYear |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/name | "Mol Biol Rep"xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/pages | "23-27"xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/title | "A novel gene STYK1/NOK is upregulated in estrogen receptor-alpha negative estrogen receptor-beta positive breast cancer cells following estrogen treatment."xsd:string |
http://purl.uniprot.org/citations/17415682 | http://purl.uniprot.org/core/volume | "35"xsd:string |
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