| http://purl.uniprot.org/citations/17440615 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17440615 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17440615 | http://www.w3.org/2000/01/rdf-schema#comment | "The survival of vertebrate species is dependent on the ability of individuals to adequately interact with each other, a function often mediated by the olfactory system. Diverse olfactory receptor repertoires are used by this system to recognize chemicals. Among these receptors, the V1rs, encoded by a very large gene family in most mammals, are able to detect pheromones. Teleosts, which also express V1r receptors, possess a very limited V1r repertoire. Here, taking advantage of the possibility to unequivocally identify V1r orthologs in teleosts, we analyzed the olfactory expression and evolutionary constraints of a pair of clustered fish V1r receptor genes, V1r1 and V1r2. Orthologs of the two genes were found in zebrafish, medaka, and threespine stickleback, but a single representative was observed in tetraodontidae species. Analysis of V1r1 and V1r2 sequences from 12 different euteleost species indicate different evolutionary rates between the two paralogous genes, leading to a highly conserved V1r2 gene and a V1r1 gene under more relaxed selective constraint. Moreover, positively-selected sites were detected in specific branches of the V1r1 clade. Our results suggest a conserved agonist specificity of the V1R2 receptor between euteleost species, its loss in the tetraodontidae lineage, and the acquisition of different chemosensory characteristics for the V1R1 receptor."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0000379"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0000379"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Rodriguez I."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Rodriguez I."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Pfister P."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Pfister P."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Randall J."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Randall J."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Montoya-Burgos J.I."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/author | "Montoya-Burgos J.I."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/name | "PLoS One"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/pages | "E379"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/pages | "e379"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/title | "Divergent evolution among teleost V1r receptor genes."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/title | "Divergent evolution among teleost V1r receptor genes."xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/17440615 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17440615 |
| http://purl.uniprot.org/citations/17440615 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17440615 |