http://purl.uniprot.org/citations/17442310 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17442310 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated the expression of formyl peptide receptor (FPR) and its functional role in human bone marrow-derived mesenchymal stem cells (MSCs). We analyzed the expression of FPR by using ligand-binding assay with radio-labeled N-formyl-met-leu-phe (fMLF), and found that MSCs express FPR. FMLF stimulated intracellular calcium increase, mitogen-activated protein kinases activation, and Akt activation, which were mediated by G(i) proteins. MSCs were chemotactically migrated to fMLF. FMLF-induced MSC chemotaxis was also completely inhibited by pertussis toxin, LY294002, and PD98059, indicating the role of G(i) proteins, phosphoinositide 3-kinase, and extracellular signal regulated protein kinase. N-terminal fragment of annexin-1, Anx-1(2-26), an endogenous agonist for FPR, also induced chemotactic migration of MSCs. Thus MSCs express functional FPR, suggesting a new (patho)physiological role of FPR and its ligands in regulating MSC trafficking during induction of injured tissue repair."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2007.03.078"xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Kim J.H."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Park Y.J."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Kim M.K."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Bae Y.S."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Ryu S.H."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/author | "Min d.o. S."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/pages | "1917-1922"xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/title | "Expression and functional role of formyl peptide receptor in human bone marrow-derived mesenchymal stem cells."xsd:string |
http://purl.uniprot.org/citations/17442310 | http://purl.uniprot.org/core/volume | "581"xsd:string |
http://purl.uniprot.org/citations/17442310 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17442310 |
http://purl.uniprot.org/citations/17442310 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17442310 |
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http://purl.uniprot.org/uniprot/#_P21462-mappedCitation-17442310 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17442310 |
http://purl.uniprot.org/uniprot/P21462 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17442310 |
http://purl.uniprot.org/uniprot/B2RC44 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17442310 |