| http://purl.uniprot.org/citations/17442750 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17442750 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17442750 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17442750 | http://www.w3.org/2000/01/rdf-schema#comment | "Biochemically, the syntrophic bacteria constitute the missing link in our understanding of anaerobic flow of carbon in the biosphere. The completed genome sequence of Syntrophus aciditrophicus SB, a model fatty acid- and aromatic acid-degrading syntrophic bacterium, provides a glimpse of the composition and architecture of the electron transfer and energy-transducing systems needed to exist on marginal energy economies of a syntrophic lifestyle. The genome contains 3,179,300 base pairs and 3,169 genes where 1,618 genes were assigned putative functions. Metabolic reconstruction of the gene inventory revealed that most biosynthetic pathways of a typical Gram-negative microbe were present. A distinctive feature of syntrophic metabolism is the need for reverse electron transport; the presence of a unique Rnf-type ion-translocating electron transfer complex, menaquinone, and membrane-bound Fe-S proteins with associated heterodisulfide reductase domains suggests mechanisms to accomplish this task. Previously undescribed approaches to degrade fatty and aromatic acids, including multiple AMP-forming CoA ligases and acyl-CoA synthetases seem to be present as ways to form and dissipate ion gradients by using a sodium-based energy strategy. Thus, S. aciditrophicus, although nutritionally self-sufficient, seems to be a syntrophic specialist with limited fermentative and respiratory metabolism. Genomic analysis confirms the S. aciditrophicus metabolic and regulatory commitment to a nonconventional mode of life compared with our prevailing understanding of microbiology."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0610456104"xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0610456104"xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0610456104"xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Bhattacharyya A."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Bhattacharyya A."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Bhattacharyya A."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Campbell J.W."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Campbell J.W."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Campbell J.W."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Gunsalus R.P."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Gunsalus R.P."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Gunsalus R.P."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Kim U."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Kim U."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Kim U."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Krupp R.S."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Krupp R.S."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "Krupp R.S."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "McInerney M.J."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "McInerney M.J."xsd:string |
| http://purl.uniprot.org/citations/17442750 | http://purl.uniprot.org/core/author | "McInerney M.J."xsd:string |