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http://purl.uniprot.org/citations/17464179 | http://www.w3.org/2000/01/rdf-schema#comment | "We investigated the co-stimulatory role of a cell-surface protein, CD99. Co-ligation of CD99 and suboptimal CD3 induced T-cell activation to a level comparable to that obtained with optimal CD3 or CD3+CD28. We also noted concomitant enhancement of the earliest T-cell receptor (TCR) signaling events. In addition, co-ligation of CD99 and CD3 led to translocation of TCR complexes into the lipid raft, without concomitant migration of CD99 to the raft, and consequent enhancement of TCR zeta-mediated signal 1. These data demonstrate the unique properties of CD99 co-stimulation that distinguish this molecule from CD28 and other raft-resident co-stimulatory factors."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.org/dc/terms/identifier | "doi:10.1038/emm.2007.20"xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Lee I.S."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Park S.H."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Kim B.K."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Jung K.C."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Choi E.Y."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Oh K.I."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/author | "Ban Y.L."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/name | "Exp Mol Med"xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/pages | "176-184"xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/title | "CD99 activates T cells via a costimulatory function that promotes raft association of TCR complex and tyrosine phosphorylation of TCR zeta."xsd:string |
http://purl.uniprot.org/citations/17464179 | http://purl.uniprot.org/core/volume | "39"xsd:string |
http://purl.uniprot.org/citations/17464179 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17464179 |
http://purl.uniprot.org/citations/17464179 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17464179 |
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