| http://purl.uniprot.org/citations/17509748 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17509748 | http://www.w3.org/2000/01/rdf-schema#comment | "The heterodimeric peptide hormone relaxin acts through the novel G-protein coupled receptor LGR7 to elicit the production of cAMP in the human monocyte cell line THP-1. The very small number of receptors on the cell surface, and the lack of response in cell membranes imply the involvement of a cytoplasmic signal amplification process. Here we show that this process comprises a novel and specific tyrosine kinase activity close to the receptor, and involves neither protein kinase A, mitogen-activated protein kinase, nor phosphoinositide-3 kinase activities as major upstream components. Furthermore, this novel involvement of a tyrosine kinase activity is cell-type dependent, being largely absent from LGR7-transfected HEK293T cells, and receptor-dependent; vasoactive intestinal peptide or isoproterenol signalling in the same cells does not require this tyrosine kinase activity."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.mce.2007.04.001"xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/author | "Ivell R."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/author | "Bartsch O."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/author | "Anand-Ivell R."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/author | "Heng K."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/name | "Mol Cell Endocrinol"xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/pages | "1-13"xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/title | "Relaxin signalling in THP-1 cells uses a novel phosphotyrosine-dependent pathway."xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://purl.uniprot.org/core/volume | "272"xsd:string |
| http://purl.uniprot.org/citations/17509748 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17509748 |
| http://purl.uniprot.org/citations/17509748 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17509748 |
| http://purl.uniprot.org/uniprot/#_P04808-mappedCitation-17509748 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17509748 |
| http://purl.uniprot.org/uniprot/P04808 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17509748 |