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http://purl.uniprot.org/citations/17556548http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17556548http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17556548http://www.w3.org/2000/01/rdf-schema#comment"During cytokinesis, as dividing animal cells pull apart into two daughter cells, the final stage, termed abscission, requires breakage of the midbody, a thin membranous stalk connecting the daughter cells. This membrane fission event topologically resembles the budding of viruses, such as HIV-1, from infected cells. We found that two proteins involved in HIV-1 budding-tumor susceptibility gene 101 (Tsg101), a subunit of the endosomal sorting complex required for transport I (ESCRT-I), and Alix, an ESCRT-associated protein-were recruited to the midbody during cytokinesis by interaction with centrosome protein 55 (Cep55), a centrosome and midbody protein essential for abscission. Tsg101, Alix, and possibly other components of ESCRT-I were required for the completion of cytokinesis. Thus, HIV-1 budding and cytokinesis use a similar subset of cellular components to carry out topologically similar membrane fission events."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.org/dc/terms/identifier"doi:10.1126/science.1143422"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.org/dc/terms/identifier"doi:10.1126/science.1143422"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/author"Martin-Serrano J."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/author"Martin-Serrano J."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/author"Carlton J.G."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/author"Carlton J.G."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/pages"1908-1912"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/pages"1908-1912"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/title"Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/title"Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery."xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/volume"316"xsd:string
http://purl.uniprot.org/citations/17556548http://purl.uniprot.org/core/volume"316"xsd:string
http://purl.uniprot.org/citations/17556548http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17556548
http://purl.uniprot.org/citations/17556548http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17556548
http://purl.uniprot.org/citations/17556548http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17556548
http://purl.uniprot.org/citations/17556548http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17556548
http://purl.uniprot.org/uniprot/Q53EZ4http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/17556548
http://purl.uniprot.org/uniprot/Q99816http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/17556548