| http://purl.uniprot.org/citations/17559233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17559233 | http://www.w3.org/2000/01/rdf-schema#comment | "The yeast Saccharomyces cerevisiae produces two 14-3-3 proteins, Bmh1 and Bmh2, whose exact functions have remained unclear. Here, we performed a comprehensive proteomic analysis using multistep immunoaffinity purification and mass spectrometry and identified 271 yeast proteins that specifically bind to Bmh1 and -2 in a phosphorylation-dependent manner. The identified proteins have diverse biochemical functions and cellular roles, including cell signaling, metabolism, and cell cycle regulation. Importantly, there are a number of protein subsets that are involved in the regulation of yeast physiology through a variety of cell signaling pathways, including stress-induced transcription, cell division, and chitin synthesis at the cell wall. In fact, we found that a yeast mutant deficient in Bmh1 and -2 had defects in signal-dependent response of the MAPK (Hog1 and Mpk1) cascade and exhibited an abnormal accumulation of chitin at the bud neck. We propose that Bmh1 and -2 are common regulators of many cell signaling modules and pathways mediated by protein phosphorylation and regulate a variety of biological events by coordinately controlling the identified multiplex phosphoprotein components."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.org/dc/terms/identifier | "doi:10.1021/bi700501t"xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Ichimura T."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Ito T."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Isobe T."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Fujita T."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Sakai A."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Yamauchi Y."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Taoka M."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Song S.Y."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Kakiuchi K."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/author | "Iwago M."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/name | "Biochemistry"xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/pages | "7781-7792"xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/title | "Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://purl.uniprot.org/core/volume | "46"xsd:string |
| http://purl.uniprot.org/citations/17559233 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17559233 |
| http://purl.uniprot.org/citations/17559233 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17559233 |
| http://purl.uniprot.org/uniprot/P34730#attribution-BE90B14B0F6D6A05A3499A16952FE3C3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17559233 |
| http://purl.uniprot.org/uniprot/P29311#attribution-BE90B14B0F6D6A05A3499A16952FE3C3 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17559233 |
| http://purl.uniprot.org/uniprot/#_P53858-mappedCitation-17559233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17559233 |
| http://purl.uniprot.org/uniprot/#_P53890-mappedCitation-17559233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17559233 |
| http://purl.uniprot.org/uniprot/#_P53901-mappedCitation-17559233 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17559233 |