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http://purl.uniprot.org/citations/17560335http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17560335http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17560335http://www.w3.org/2000/01/rdf-schema#comment"To unravel the normal vasculature transcriptome and determine how it is altered by neighboring malignant cells, we compared gene expression patterns of endothelial cells derived from the blood vessels of eight normal resting tissues, five tumors, and regenerating liver. Organ-specific endothelial genes were readily identified, including 27 from brain. We also identified 25 transcripts overexpressed in tumor versus normal endothelium, including 13 that were not found in the angiogenic endothelium of regenerating liver. Most of the shared angiogenesis genes have expected roles in cell-cycle control, but those specific for tumor endothelium were primarily cell surface molecules of uncertain function. These studies reveal striking differences between physiological and pathological angiogenesis potentially important for the development of tumor-specific, vascular-targeted therapies."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.org/dc/terms/identifier"doi:10.1016/j.ccr.2007.04.017"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.org/dc/terms/identifier"doi:10.1016/j.ccr.2007.04.017"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Stevens J."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Stevens J."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Yang M.Y."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Yang M.Y."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Logsdon D."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Logsdon D."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Seaman S."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Seaman S."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"St Croix B."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"St Croix B."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Graff-Cherry C."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/author"Graff-Cherry C."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/name"Cancer Cell"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/name"Cancer Cell"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/pages"539-554"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/pages"539-554"xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/title"Genes that distinguish physiological and pathological angiogenesis."xsd:string
http://purl.uniprot.org/citations/17560335http://purl.uniprot.org/core/title"Genes that distinguish physiological and pathological angiogenesis."xsd:string