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http://purl.uniprot.org/citations/17563365http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17563365http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17563365http://www.w3.org/2000/01/rdf-schema#comment"The Arabidopsis thaliana genome contains five genes that encode two pore K+ (TPK) channels. The most abundantly expressed isoform of this family, TPK1, is expressed at the tonoplast where it mediates K+ -selective currents between cytoplasmic and vacuolar compartments. TPK1 open probability depends on both cytoplasmic Ca2+ and cytoplasmic pH but not on the tonoplast membrane voltage. The channel shows intrinsic rectification and can be blocked by Ba2+, tetraethylammonium, and quinine. TPK1 current was found in all shoot cell types and shows all of the hallmarks of the previously described vacuolar K (VK) tonoplast channel characterized in guard cells. Characterization of TPK1 loss-of-function mutants and TPK1-overexpressing plants shows that TPK1 has a role in intracellular K+ homeostasis affecting seedling growth at high and low ambient K+ levels. In stomata, TPK1 function is consistent with vacuolar K+ release, and removal of this channel leads to slower stomatal closure kinetics. During germination, TPK1 contributes to the radicle development through vacuolar K+ deposition to provide expansion growth or in the redistribution of essential minerals."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.org/dc/terms/identifier"doi:10.1073/pnas.0702595104"xsd:string
http://purl.uniprot.org/citations/17563365http://purl.org/dc/terms/identifier"doi:10.1073/pnas.0702595104"xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Voelker C."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Voelker C."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Maathuis F.J."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Maathuis F.J."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Czempinski K."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Czempinski K."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Gobert A."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Gobert A."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Isayenkov S."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/author"Isayenkov S."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/pages"10726-10731"xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/pages"10726-10731"xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/title"The two-pore channel TPK1 gene encodes the vacuolar K+ conductance and plays a role in K+ homeostasis."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/title"The two-pore channel TPK1 gene encodes the vacuolar K+ conductance and plays a role in K+ homeostasis."xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/volume"104"xsd:string
http://purl.uniprot.org/citations/17563365http://purl.uniprot.org/core/volume"104"xsd:string