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http://purl.uniprot.org/citations/1756736http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1756736http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/1756736http://www.w3.org/2000/01/rdf-schema#comment"The wis1+ gene encodes a newly identified mitotic control element in Schizosaccharomyces pombe. It was isolated by virtue of its interaction with the mitotic control genes cdc25, wee1 and win1. The wis1+ gene potentially encodes a 66 kDa protein with homology to the serine/threonine family of protein kinases. wis1+ plays an important role in the regulation of entry into mitosis, as it shares with cdc25+ and nim1+/cdr1+ the property of inducing mitosis in a dosage-dependent manner. Increased levels of wis1+ expression cause mitotic initiation to occur at a reduced cell size. Loss of wis1+ function does not prevent vegetative growth and division, though wis1-cells show an elongated morphology, indicating that their entry into mitosis and cell division is delayed relative to wild type cells. wis1-cells undergo a rapid reduction of viability upon entry into stationary phase, suggesting a role for wis1+ in the integration of nutritional sensing with the control over entry into mitosis."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1991.tb05007.x"xsd:string
http://purl.uniprot.org/citations/1756736http://purl.org/dc/terms/identifier"doi:10.1002/j.1460-2075.1991.tb05007.x"xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/author"Fantes P.A."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/author"Fantes P.A."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/author"Warbrick E."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/author"Warbrick E."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/name"EMBO J."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/pages"4291-4299"xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/pages"4291-4299"xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/title"The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/title"The wis1 protein kinase is a dosage-dependent regulator of mitosis in Schizosaccharomyces pombe."xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/1756736http://purl.uniprot.org/core/volume"10"xsd:string
http://purl.uniprot.org/citations/1756736http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1756736
http://purl.uniprot.org/citations/1756736http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/1756736
http://purl.uniprot.org/citations/1756736http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1756736
http://purl.uniprot.org/citations/1756736http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/1756736
http://purl.uniprot.org/uniprot/P33886http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/1756736
http://purl.uniprot.org/uniprot/P33886#attribution-FE7536C496DB2EB4A97E97A3758C7770http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/1756736