http://purl.uniprot.org/citations/17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17586499 | http://www.w3.org/2000/01/rdf-schema#comment | "The yeast glucose sensors Rgt2 and Snf3 generate a signal in response to glucose that leads to degradation of Mth1 and Std1, thereby relieving repression of Rgt1-repressed genes such as the glucose transporter genes (HXT). Mth1 and Std1 are degraded via the Yck1/2 kinase-SCF(Grr1)-26S proteasome pathway triggered by the glucose sensors. Here, we show that RGT2-1 promotes ubiquitination and subsequent degradation of Mth1 and Std1 regardless of the presence of glucose. Site-specific mutagenesis reveals that the conserved lysine residues of Mth1 and Std1 might serve as attachment sites for ubiquitin, and that the potential casein kinase (Yck1/2) sites of serine phosphorylation might control their ubiquitination. Finally, we show that active Snf1 protein kinase in high glucose prevents degradation of Mth1 and Std1."xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2007.06.013"xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/author | "Kim J.H."xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/author | "Pasula S."xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/author | "Jouandot D."xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/pages | "3230-3234"xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/title | "Biochemical evidence for glucose-independent induction of HXT expression in Saccharomyces cerevisiae."xsd:string |
http://purl.uniprot.org/citations/17586499 | http://purl.uniprot.org/core/volume | "581"xsd:string |
http://purl.uniprot.org/citations/17586499 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17586499 |
http://purl.uniprot.org/citations/17586499 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17586499 |
http://purl.uniprot.org/uniprot/#_A0A8H4F8Q3-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_A0A8H8UMF6-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_A0A6A5Q1W6-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_A0A6A5Q2C5-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_P38990-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_Q12300-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_P10870-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_P06782-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_Q00816-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_P35198-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/#_Q02794-mappedCitation-17586499 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17586499 |
http://purl.uniprot.org/uniprot/P38990 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17586499 |