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http://purl.uniprot.org/citations/17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17586499http://www.w3.org/2000/01/rdf-schema#comment"The yeast glucose sensors Rgt2 and Snf3 generate a signal in response to glucose that leads to degradation of Mth1 and Std1, thereby relieving repression of Rgt1-repressed genes such as the glucose transporter genes (HXT). Mth1 and Std1 are degraded via the Yck1/2 kinase-SCF(Grr1)-26S proteasome pathway triggered by the glucose sensors. Here, we show that RGT2-1 promotes ubiquitination and subsequent degradation of Mth1 and Std1 regardless of the presence of glucose. Site-specific mutagenesis reveals that the conserved lysine residues of Mth1 and Std1 might serve as attachment sites for ubiquitin, and that the potential casein kinase (Yck1/2) sites of serine phosphorylation might control their ubiquitination. Finally, we show that active Snf1 protein kinase in high glucose prevents degradation of Mth1 and Std1."xsd:string
http://purl.uniprot.org/citations/17586499http://purl.org/dc/terms/identifier"doi:10.1016/j.febslet.2007.06.013"xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/author"Kim J.H."xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/author"Pasula S."xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/author"Jouandot D."xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/name"FEBS Lett"xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/pages"3230-3234"xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/title"Biochemical evidence for glucose-independent induction of HXT expression in Saccharomyces cerevisiae."xsd:string
http://purl.uniprot.org/citations/17586499http://purl.uniprot.org/core/volume"581"xsd:string
http://purl.uniprot.org/citations/17586499http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17586499
http://purl.uniprot.org/citations/17586499http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17586499
http://purl.uniprot.org/uniprot/#_A0A8H4F8Q3-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_A0A8H8UMF6-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_A0A6A5Q1W6-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_A0A6A5Q2C5-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_P38990-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_Q12300-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_P10870-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_P06782-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_Q00816-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_P35198-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/#_Q02794-mappedCitation-17586499http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17586499
http://purl.uniprot.org/uniprot/P38990http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17586499