http://purl.uniprot.org/citations/17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17588941 | http://www.w3.org/2000/01/rdf-schema#comment | "Netrins were first identified as neural guidance molecules, acting through receptors that are members of the DCC and UNC-5 family. All netrins share structural homology to the laminin N-terminal domains and the laminin epidermal growth factor-like domains of laminin short arms. Laminins use these domains to self-assemble into complex networks. Here we demonstrate that netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms. The binding is mediated through the laminin N-terminal domain of netrin-4. In contrast to netrin-4, other members of the netrin family do not bind to these laminin short arms. Moreover, a truncated form of netrin-4 completely inhibits laminin-111 self-assembly in vitro, and full-length netrin-4 can partially disrupt laminin self-interactions. When added to explant cultures, netrin-4 retards salivary gland branching morphogenesis."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m703137200"xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Li Y."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Koch M."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Bose K."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Paulsson M."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Brunken W.J."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Smyth N."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Maertens B."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/author | "Schneiders F.I."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/pages | "23750-23758"xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/title | "Binding of netrin-4 to laminin short arms regulates basement membrane assembly."xsd:string |
http://purl.uniprot.org/citations/17588941 | http://purl.uniprot.org/core/volume | "282"xsd:string |
http://purl.uniprot.org/citations/17588941 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17588941 |
http://purl.uniprot.org/citations/17588941 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17588941 |
http://purl.uniprot.org/uniprot/Q9JI33#attribution-ECA23FC72ED4FB0A95AC66C42AA70840 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_P11047-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_B0QZL0-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_A2ATM9-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_O15230-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_D3Z053-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |
http://purl.uniprot.org/uniprot/#_F8VQJ3-mappedCitation-17588941 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17588941 |