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http://purl.uniprot.org/citations/17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17588941http://www.w3.org/2000/01/rdf-schema#comment"Netrins were first identified as neural guidance molecules, acting through receptors that are members of the DCC and UNC-5 family. All netrins share structural homology to the laminin N-terminal domains and the laminin epidermal growth factor-like domains of laminin short arms. Laminins use these domains to self-assemble into complex networks. Here we demonstrate that netrin-4 is a component of basement membranes and is integrated into the laminin polymer via interactions with the laminin gamma1 andgamma3 short arms. The binding is mediated through the laminin N-terminal domain of netrin-4. In contrast to netrin-4, other members of the netrin family do not bind to these laminin short arms. Moreover, a truncated form of netrin-4 completely inhibits laminin-111 self-assembly in vitro, and full-length netrin-4 can partially disrupt laminin self-interactions. When added to explant cultures, netrin-4 retards salivary gland branching morphogenesis."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m703137200"xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Li Y."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Koch M."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Bose K."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Paulsson M."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Brunken W.J."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Smyth N."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Maertens B."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/author"Schneiders F.I."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/name"J Biol Chem"xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/pages"23750-23758"xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/title"Binding of netrin-4 to laminin short arms regulates basement membrane assembly."xsd:string
http://purl.uniprot.org/citations/17588941http://purl.uniprot.org/core/volume"282"xsd:string
http://purl.uniprot.org/citations/17588941http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17588941
http://purl.uniprot.org/citations/17588941http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17588941
http://purl.uniprot.org/uniprot/Q9JI33#attribution-ECA23FC72ED4FB0A95AC66C42AA70840http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_P11047-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_B0QZL0-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_A2ATM9-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_O15230-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_D3Z053-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941
http://purl.uniprot.org/uniprot/#_F8VQJ3-mappedCitation-17588941http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17588941