| http://purl.uniprot.org/citations/17589850 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17589850 | http://www.w3.org/2000/01/rdf-schema#comment | "Rheumatoid arthritis (RA) in Thai population is significantly associated with HLA-DR4 shared epitope (SE) alleles, particularly with DRB1*0405 (P = 0.00004, OR = 3.84, 95% CI = 1.93, 7.7). In addition, tumor necrosis factor-alpha (TNF-alpha) gene -863A alleles were found to be significantly increased in 77 RA patients compared to 162 healthy controls (P = 0.03, OR = 1.73, 95% CI = 1.05, 2.87). Interestingly, TNF-863 AC and SE have a synergistic effect on the susceptibility to RA. The OR for the presence of both risk factors (DR4 SE and -863 AC) was cumulative: 15.4 (95% CI = 3.75, 73.6) while the separate OR of DR4 SE and -863 AC were 3.84 and 2.36, respectively. The TNF was not associated with the clinical manifestation and severity of Thai RA patients. However, a highly significant association was found between RF positivity, one marker for severity, and RA patients with DR4 SE (P = 0.0005, OR = 9.42, 95% CI = 2.26, 45.27)."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.org/dc/terms/identifier | "doi:10.1007/s00296-007-0392-8"xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/author | "Charoenwongse P."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/author | "Deesomchok U."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/author | "Hirankarn N."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/author | "Nakkuntod J."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/author | "Duangchalermwong P."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/name | "Rheumatol Int"xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/pages | "161-165"xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/title | "The association of DRB1*04 share epitope alleles and tumor necrosis factor-alpha gene polymorphism (-863) with susceptibility to rheumatoid arthritis in Thai."xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/17589850 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17589850 |
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| http://purl.uniprot.org/uniprot/#_A0A141AZI3-mappedCitation-17589850 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17589850 |
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