| http://purl.uniprot.org/citations/17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17592038 | http://www.w3.org/2000/01/rdf-schema#comment | "microRNAs (miRNAs) serve as post-transcriptional regulators of gene expression, by guiding effector complexes (miRNPs) to target RNAs. Although considerable progress has been made in computational methods to identify miRNA targets, only a relatively limited assessment of their ability to function in vivo has been reported. Here we describe an alternative approach to miRNA target identification based on a biochemical method for purifying miRNP complexes with associated miRNAs and bound mRNA targets. Microarray analysis revealed a high degree of enrichment for miRNA complementary sites in the 3'UTRs of the miRNP-associated mRNAs. mRNAs specifically associated with an individual miRNA were identified by comparing the miRNP-associated mRNAs from wild-type flies and mutant flies lacking miR-1, and their regulation by the miRNA was validated. This approach provides a means to identify functional miRNA targets based on their physical interaction in vivo."xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.org/dc/terms/identifier | "doi:10.1261/rna.563707"xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/author | "Teleman A.A."xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/author | "Cohen S.M."xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/author | "Easow G."xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/name | "RNA"xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/pages | "1198-1204"xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/title | "Isolation of microRNA targets by miRNP immunopurification."xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/17592038 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17592038 |
| http://purl.uniprot.org/citations/17592038 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17592038 |
| http://purl.uniprot.org/uniprot/#_A0A0B4KI57-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_A0A0B4K7R2-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_C6TP98-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_E1JJR9-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_B7Z067-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_B7Z068-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_Q32KD4-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_M9PC08-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_M9PFK2-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_M9PFK7-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_M9PFY9-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |
| http://purl.uniprot.org/uniprot/#_Q24475-mappedCitation-17592038 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/17592038 |