| http://purl.uniprot.org/citations/17596443 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17596443 | http://www.w3.org/2000/01/rdf-schema#comment | "Neuronal circuits including medium spiny neurons (MSNs) in the nucleus accumbens (NAc) and melanin-concentrating hormone (MCH)-containing neurons in the lateral hypothalamic area (LHA) are hypothesized to play an important role in hedonic feeding. A reciprocal connection between NAc MSNs and MCH-containing neurons is proposed to form a neuronal circuit that is involved in hedonic feeding. Although NAc MSNs have been shown to receive projection from MCH-containing neurons, it is not known whether MCH-containing neurons in the LHA also receive direct inputs from NAc MSNs. Here, we developed a genetic approach that allows us to visualize almost all striatal MSNs including NAc MSNs. We demonstrate that striatal MSNs terminate in a distinct region within the anterior LHA, and that the terminal area of striatal MSNs in this region contains glutamatergic neurons and is distinctly separate from orexin/hypocretin- or MCH-containing neurons. These observations suggest that NAc MSNs do not directly innervate MCH-containing neurons, but may indirectly signal MCH-containing neurons via glutamatergic neurons in the anterior LHA."xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.org/dc/terms/identifier | "doi:10.1523/jneurosci.0514-07.2007"xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/author | "Sano H."xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/author | "Yokoi M."xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/name | "J Neurosci"xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/pages | "6948-6955"xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/title | "Striatal medium spiny neurons terminate in a distinct region in the lateral hypothalamic area and do not directly innervate orexin/hypocretin- or melanin-concentrating hormone-containing neurons."xsd:string |
| http://purl.uniprot.org/citations/17596443 | http://purl.uniprot.org/core/volume | "27"xsd:string |
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