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http://purl.uniprot.org/citations/17604721http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17604721http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17604721http://www.w3.org/2000/01/rdf-schema#comment"COPII-coated vesicles export newly synthesized proteins from the endoplasmic reticulum. The COPII coat consists of the Sec23/24-Sar1 complex that selects cargo and the Sec13/31 assembly unit that can polymerize into an octahedral cage and deform the membrane into a bud. Crystallographic analysis of the assembly unit reveals a 28 nm long rod comprising a central alpha-solenoid dimer capped by two beta-propeller domains at each end. We construct a molecular model of the COPII cage by fitting Sec13/31 crystal structures into a recently determined electron microscopy density map. The vertex geometry involves four copies of the Sec31 beta-propeller that converge through their axial ends; there is no interdigitation of assembly units of the kind seen in clathrin cages. We also propose that the assembly unit has a central hinge-an arrangement of interlocked alpha-solenoids-about which it can bend to adapt to cages of variable curvature."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2007.05.036"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.org/dc/terms/identifier"doi:10.1016/j.cell.2007.05.036"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Goldberg J."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Goldberg J."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Bi X."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Bi X."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Mancias J.D."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Mancias J.D."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Fath S."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/author"Fath S."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/pages"1325-1336"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/pages"1325-1336"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/title"Structure and organization of coat proteins in the COPII cage."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/title"Structure and organization of coat proteins in the COPII cage."xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/volume"129"xsd:string
http://purl.uniprot.org/citations/17604721http://purl.uniprot.org/core/volume"129"xsd:string
http://purl.uniprot.org/citations/17604721http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17604721
http://purl.uniprot.org/citations/17604721http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17604721