| http://purl.uniprot.org/citations/17618624 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17618624 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17618624 | http://www.w3.org/2000/01/rdf-schema#comment | "Autophagy depends on the activity of phosphoinositide-3 kinase class III to generate PI(3)P. We identified the human WIPI protein family of PI(3)P-binding factors and showed that WIPI-1 (Atg18) is linked to autophagy in human cells. Induction of autophagy by rapamycin, gleevec, thapsigargin and amino acid deprivation led to an accumulation of WIPI-1 at LC3-positive membrane structures (WIPI-1 puncta-formation), suggested to represent autophagosomal isolation membranes. WIPI-1 puncta-formation is inhibited by wortmannin and LY294002, and PI(3)P-binding-deficient WIPI-1 is puncta-formation-incompetent. Quantification of WIPI-1 puncta should be suitable to assay mammalian autophagy."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2007.06.040"xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2007.06.040"xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Berg C."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Berg C."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Stierhof Y.D."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Stierhof Y.D."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Proikas-Cezanne T."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Proikas-Cezanne T."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Nordheim A."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Nordheim A."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Ruckerbauer S."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/author | "Ruckerbauer S."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/pages | "3396-3404"xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/pages | "3396-3404"xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/title | "Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/title | "Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy."xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/volume | "581"xsd:string |
| http://purl.uniprot.org/citations/17618624 | http://purl.uniprot.org/core/volume | "581"xsd:string |