| http://purl.uniprot.org/citations/17622474 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17622474 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17622474 | http://www.w3.org/2000/01/rdf-schema#comment | "PCP-2 is a human receptor-like protein tyrosine phosphatase and a member of the MAM domain family cloned in human pancreatic adenocarcinoma cells. Previous studies showed that PCP-2 directly interacted with beta-catenin through the juxtamembrane domain, dephosphorylated beta-catenin and played an important role in the regulation of cell adhesion. Recent study showed that PCP-2 was also involved in the repression of beta-catenin-induced transcriptional activity. Here we describe the interactions of PCP-2 with the beta3A subunit of adaptor protein (AP)-3 and sorting nexin (SNX) 3. These protein complexes were detected using the yeast two-hybrid assay with the juxtamembrane and membrane-proximal catalytic domain of PCP-2 as "bait" Both AP-3 and SNX3 are molecules involved in intracellular trafficking of membrane receptors. The association between the beta3A subunit of AP-3 and PCP-2 was further confirmed in mammalian cells. Our results suggested a possible mechanism of intracellular trafficking of PCP-2 mediated by AP-3 and SNX3 which might participate in the regulation of PCP-2 functions."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1745-7270.2007.00303.x"xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1745-7270.2007.00303.x"xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Dong H."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Dong H."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Jin W."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Jin W."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Shen Y."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Shen Y."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Xu X."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Xu X."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Yuan H."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Yuan H."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Wang H.-Y."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/author | "Wang H.-Y."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/name | "Acta Biochim. Biophys. Sin."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/name | "Acta Biochim. Biophys. Sin."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/pages | "540-546"xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/pages | "540-546"xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/title | "Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2."xsd:string |
| http://purl.uniprot.org/citations/17622474 | http://purl.uniprot.org/core/title | "Involvement of beta3A subunit of adaptor protein-3 in intracellular trafficking of receptor-like protein tyrosine phosphatase PCP-2."xsd:string |