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http://purl.uniprot.org/citations/17626041http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17626041http://www.w3.org/2000/01/rdf-schema#comment"The Cockayne Syndrome group B (CSB) protein plays important roles in transcription, transcription-coupled nucleotide excision repair and base excision DNA repair. c-Abl kinase also plays a role in DNA repair as a regulator/coordinator of the DNA damage response. This study presents evidence that the N-terminal region of CSB interacts with the SH3 domain of c-Abl in vitro and in vivo. In addition, c-Abl kinase phosphorylates CSB at Tyr932. The subcellular localization of CSB to the nucleus and nucleolus is altered after phosphorylation by c-Abl. c-Abl-dependent phosphorylation of CSB increased in cells treated with hydrogen peroxide and decreased in cells pre-treated with STI-571, a c-Abl-specific protein kinase inhibitor. Activation of the c-Abl kinase in response to oxidative damage is not observed in CSB null cells. These results suggest that c-Abl and CSB may regulate each other in a reciprocal manner in response to oxidative stress."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.org/dc/terms/identifier"doi:10.1093/nar/gkm386"xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Kufe D."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Imam S.Z."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Bohr V.A."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Cheng W.H."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Stevnsner T."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Indig F.E."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/author"Saxena S.P."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/name"Nucleic Acids Res"xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/pages"4941-4951"xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/title"Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase."xsd:string
http://purl.uniprot.org/citations/17626041http://purl.uniprot.org/core/volume"35"xsd:string
http://purl.uniprot.org/citations/17626041http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17626041
http://purl.uniprot.org/citations/17626041http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17626041
http://purl.uniprot.org/uniprot/P00519#attribution-1F1177F296D78FB4FC4B3C85569AEE04http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/P00519#attribution-A0B79FB0C9029F874B9BE9BEFD1E565Ahttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/P00520#attribution-598E2908DA221AEA135ACB7A17A8362Bhttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/Q03468#attribution-1F1177F296D78FB4FC4B3C85569AEE04http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/#_A0A0A6YVY6-mappedCitation-17626041http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/#_A0A0A6YXS9-mappedCitation-17626041http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/#_A0A0A6YY65-mappedCitation-17626041http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17626041
http://purl.uniprot.org/uniprot/#_A2AV23-mappedCitation-17626041http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17626041