| http://purl.uniprot.org/citations/17628282 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17628282 | http://www.w3.org/2000/01/rdf-schema#comment | "We previously reported the identification of a putative juvenile hormone esterase (JHE) binding protein DmP29 in Drosophila melanogaster and its primary localization to the mitochondria [Liu, Z., Ho, L., Bonning, B.C., 2007. Localization of a Drosophila melanogaster homolog of the putative juvenile hormone esterase binding protein of Manduca sexta. Insect Biochem. Mol. Biol. 37(2), 155-163]. To further characterize DmP29, we identified potential ligands of this protein. Recombinant DmP29 was shown by ligand blot and co-immunoprecipitation analyses to bind recombinant JHE as well as to larval serum proteins (LSP). The possible biological relevance of the in vitro DmP29-JHE interaction is provided by detection of JHE activity in D. melanogaster mitochondrial fractions; 0.48 nmol JH hydrolyzed/min/mg mitochondrial protein, 97% of which was inhibited by the JHE-specific inhibitor OTFP. However, the DmP29-LSP interactions may not be biologically relevant. Given the high abundance, and "sticky" nature of these proteins, interaction of DmP29 with LSP may result from non-specific associations. No DmP29 interactions with non-specific esterases were detected by co-immunoprecipitation analyses. The potential role of DmP29 as a chaperone of JHE is discussed."xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.ibmb.2007.04.005"xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/author | "Bonning B.C."xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/author | "Pal N."xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/name | "Insect Biochem Mol Biol"xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/pages | "838-846"xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/title | "Potential ligands of DmP29, a putative juvenile hormone esterase binding protein of Drosophila melanogaster."xsd:string |
| http://purl.uniprot.org/citations/17628282 | http://purl.uniprot.org/core/volume | "37"xsd:string |
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