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http://purl.uniprot.org/citations/17641165http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17641165http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17641165http://www.w3.org/2000/01/rdf-schema#comment"Understanding why some people establish and maintain effective control of HIV-1 and others do not is a priority in the effort to develop new treatments for HIV/AIDS. Using a whole-genome association strategy, we identified polymorphisms that explain nearly 15% of the variation among individuals in viral load during the asymptomatic set-point period of infection. One of these is found within an endogenous retroviral element and is associated with major histocompatibility allele human leukocyte antigen (HLA)-B*5701, whereas a second is located near the HLA-C gene. An additional analysis of the time to HIV disease progression implicated two genes, one of which encodes an RNA polymerase I subunit. These findings emphasize the importance of studying human genetic variation as a guide to combating infectious agents."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.org/dc/terms/identifier"doi:10.1126/science.1143767"xsd:string
http://purl.uniprot.org/citations/17641165http://purl.org/dc/terms/identifier"doi:10.1126/science.1143767"xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Colombo S."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Colombo S."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Letvin N.L."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Letvin N.L."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Zhang K."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Zhang K."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Haynes B.F."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Haynes B.F."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Antonarakis S.E."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Antonarakis S.E."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Telenti A."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Telenti A."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"McMichael A.J."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"McMichael A.J."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Goldstein D.B."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Goldstein D.B."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"De Luca A."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"De Luca A."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Weale M."xsd:string
http://purl.uniprot.org/citations/17641165http://purl.uniprot.org/core/author"Weale M."xsd:string