| http://purl.uniprot.org/citations/17643121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17643121 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/17643121 | http://www.w3.org/2000/01/rdf-schema#comment | "Breast cancer-1 (BRCA1) participates in the DNA damage response. However, the mechanism by which BRCA1 is recruited to DNA damage sites remains elusive. Recently, we have demonstrated that a ubiquitin-binding protein, RAP80, is required for DNA damage-induced BRCA1 translocation. Here we identify another component, CCDC98, in the BRCA1-RAP80 complex. CCDC98 mediates BRCA1's association with RAP80. Moreover, CCDC98 controls both DNA damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation. Together, our results demonstrate that CCDC98 is a BRCA1 binding partner that mediates BRCA1 function in response to DNA damage."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb1279"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.org/dc/terms/identifier | "doi:10.1038/nsmb1279"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Liu Z."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Wu J."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Wu J."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/author | "Yu X."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/name | "Nat. Struct. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/name | "Nat. Struct. Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/pages | "716-720"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/pages | "716-720"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/title | "CCDC98 targets BRCA1 to DNA damage sites."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/title | "CCDC98 targets BRCA1 to DNA damage sites."xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/17643121 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17643121 |
| http://purl.uniprot.org/citations/17643121 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17643121 |
| http://purl.uniprot.org/citations/17643121 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17643121 |
| http://purl.uniprot.org/citations/17643121 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/17643121 |