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| http://purl.uniprot.org/citations/17646657 | http://www.w3.org/2000/01/rdf-schema#comment | "Cultures of neuroblasts that generate abundant neurons were established from Drosophila embryos to study silencing of genes by RNA interference (RNAi). Cultured cells expressed ELAV, a marker of neurons, Futsch, a marker of neurites, and Synapsin, Synaptobrevin, and Synaptogamin, proteins involved in neurotransmitter secretion. Conditions were found for efficient transfection of cells with siRNAs for ELAV or the insulin-like receptor, which resulted in marked decreases in neurons that express ELAV and Futsch. Cells also were successfully transfected with long-chain Sox-Neuro dsRNA resulting in a 55% reduction of neurons expressing Futsch. The results suggest that this cultured neural cell system can be used to study RNAi-dependent silencing of genes involved in many kinds of neural functions."xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0704299104"xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/author | "Sharma S.K."xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/author | "Nirenberg M."xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/pages | "12925-12930"xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/title | "Silencing of genes in cultured Drosophila neurons by RNA interference."xsd:string |
| http://purl.uniprot.org/citations/17646657 | http://purl.uniprot.org/core/volume | "104"xsd:string |
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