http://purl.uniprot.org/citations/17657435 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/17657435 | http://www.w3.org/2000/01/rdf-schema#comment | "Experiments were performed on Norwegian rats selected over more than 59 generations for high and low levels of high-affective defensive aggressivity and on highly aggressive (offensive) Tg8 mice with irreversible monoamine oxidase A knockout. There were significant differences in the functional state and expression of 5-HT(1A) receptors between highly aggressive and non-aggressive animals. Functional activity assessed in terms of hypothermia evoked by a 5-HT(1A) agonist was significantly greater in non-aggressive rats and mice than in aggressive animals. The high level of functional activity in non-aggressive rats coincided with a greater level of expression of 5-HT(1A) receptors in the midbrain. The level of 5-HT(1A) receptor mRNA in aggressive mice was unchanged in the midbrain and hypothalamus and was increased in the frontal cortex and amygdaloid complex. These results led to the conclusion that 5-HT(1A) receptors play a significant role in the mechanisms of genetic predisposition to aggressive behavior."xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11055-007-0062-z"xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/author | "Naumenko V.S."xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/author | "Popova N.K."xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/author | "Plyusnina I.Z."xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/date | "2007"xsd:gYear |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/name | "Neurosci Behav Physiol"xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/pages | "631-635"xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/title | "Involvement of brain serotonin 5-HT1A receptors in genetic predisposition to aggressive behavior."xsd:string |
http://purl.uniprot.org/citations/17657435 | http://purl.uniprot.org/core/volume | "37"xsd:string |
http://purl.uniprot.org/citations/17657435 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/17657435 |
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http://purl.uniprot.org/uniprot/Q64264 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17657435 |
http://purl.uniprot.org/uniprot/Q8BZP1 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/17657435 |