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http://purl.uniprot.org/citations/17657435http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/17657435http://www.w3.org/2000/01/rdf-schema#comment"Experiments were performed on Norwegian rats selected over more than 59 generations for high and low levels of high-affective defensive aggressivity and on highly aggressive (offensive) Tg8 mice with irreversible monoamine oxidase A knockout. There were significant differences in the functional state and expression of 5-HT(1A) receptors between highly aggressive and non-aggressive animals. Functional activity assessed in terms of hypothermia evoked by a 5-HT(1A) agonist was significantly greater in non-aggressive rats and mice than in aggressive animals. The high level of functional activity in non-aggressive rats coincided with a greater level of expression of 5-HT(1A) receptors in the midbrain. The level of 5-HT(1A) receptor mRNA in aggressive mice was unchanged in the midbrain and hypothalamus and was increased in the frontal cortex and amygdaloid complex. These results led to the conclusion that 5-HT(1A) receptors play a significant role in the mechanisms of genetic predisposition to aggressive behavior."xsd:string
http://purl.uniprot.org/citations/17657435http://purl.org/dc/terms/identifier"doi:10.1007/s11055-007-0062-z"xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/author"Naumenko V.S."xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/author"Popova N.K."xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/author"Plyusnina I.Z."xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/date"2007"xsd:gYear
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/name"Neurosci Behav Physiol"xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/pages"631-635"xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/title"Involvement of brain serotonin 5-HT1A receptors in genetic predisposition to aggressive behavior."xsd:string
http://purl.uniprot.org/citations/17657435http://purl.uniprot.org/core/volume"37"xsd:string
http://purl.uniprot.org/citations/17657435http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/17657435
http://purl.uniprot.org/citations/17657435http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/17657435
http://purl.uniprot.org/uniprot/#_Q64264-mappedCitation-17657435http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17657435
http://purl.uniprot.org/uniprot/#_Q8BZP1-mappedCitation-17657435http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/17657435
http://purl.uniprot.org/uniprot/Q64264http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17657435
http://purl.uniprot.org/uniprot/Q8BZP1http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/17657435